Nebulized Antibiotics
نویسندگان
چکیده
منابع مشابه
Bronchial response to nebulized antibiotics in children with cystic fibrosis.
Nebulized antibiotics are being used increasingly in children with cystic fibrosis. We assessed the effect of nebulized antibiotic solutions of varying tonicity on lung function in 12 children aged 5-15 yrs with cystic fibrosis. Baseline forced expiratory volume in one second and (FEV1) was measured, followed by a single nebulization of normal saline (272 mosmol.kg-1), tobramycin (248 mosmol.kg...
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I read with interest the recent systematic review of nebulized antibiotics for ventilator-associated pneumonia [1]. I congratulate and applaud Zampieri and colleagues’ important work, but several important issues should be noted. First, there is one important methodological issue with the review. The data from randomized controlled trials and observational studies were inappropriately pooled to...
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Nebulized antibiotic therapy directly targets airways and lung parenchyma resulting in high local concentrations and potentially lower systemic toxicities. Experimental and clinical studies have provided evidence for elevated lung concentrations and rapid bacterial killing following the administration of nebulized antibiotics during mechanical ventilation. Delivery of high concentrations of ant...
متن کاملNebulized antibiotics for ventilator-associated pneumonia: a systematic review and meta-analysis
INTRODUCTION Nebulized antibiotics are a promising new treatment option for ventilator-associated pneumonia. However, more evidence of the benefit of this therapy is required. METHODS The Medline, Scopus, EMBASE, Biological Abstracts, CAB Abstracts, Food Science and Technology Abstracts, CENTRAL, Scielo and Lilacs databases were searched to identify randomized controlled trials or matched obs...
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Objective. Nebulized budesonide and nebulized adrenaline have been shown to be effective in the treatment of moderately severe croup. However, there has been no direct comparison of these therapies. We undertook a multicenter, randomized, double-blind, parallel group study in 66 hospitalized children with viral or spasmodic croup. Methods. Children 0.5 to 6 years of age were assessed using a va...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2019
ISSN: 0003-3022
DOI: 10.1097/aln.0000000000002824